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Walks & Field Notes:

Great Rock Bight with Tom Vogl

By Russell Hoxsie

What commences with a pale green chameleon, a tiny cordon bleu, goldfish, and a variety of special chickens, which at times roams free over the panhandle in West Tisbury?
I arrive at the Long-Vogl residence an hour early for my walk with Tom Vogl. As if I were on time to the minute, Katherine Long invites me on a tour of her remarkable home containing an aviary, a weaving area complete with loom, and a living room lined with shelves holding 800 cookbooks. A library ladder stands alongside to reach the topmost volumes. Their sunroom is home to a shy, pale green chameleon and small blue finch. The field out back holds horse-trough tanks for goldfish, plus house and coops for the fowl - silver Dorkings, which Julius Caesar brought from Rome and were named for the English town; mottled Houdans; gold-penciled Hamburgs (called "hats"); crested Polish; and finally, Buttercups (hardly distinguishable from the "hats"). This is the start of my afternoon with Katherine's husband, Tom, who arrives as several of the chickens begin to flit past me at the gate into the great outdoors.
I've known Tom Vogl for three or four years, meeting Friday mornings at the hospital for medical rounds. He is a quiet sort, says little at these conferences, but is a store of knowledge about computers, which he has demonstrated to me when I've crashed one way or another. I hope to pick his brains about his life as a scientist. We choose Great Rock Bight, the Martha's Vineyard Land Bank preserve off North Road in Chilmark, because he's never visited there. Early fog has blown away, skies are mostly clear, wind is up, and temperature is 70 degrees. We launch the walk and conversation.
"Using the retro-spectroscope," he says, "I guess I spent almost all my life being involved with photons." While an undergraduate at Columbia in New York, he studied physics, chemistry, geology, and enough upper level courses to graduate. His student research with crystals involved the study of uranium ore, sklodowskite, named for Marie Curie's maiden name. "At one point, I was invited back at a 'munificent' salary to work on my advanced degree. They only wanted me because I knew how to install sinks," he says with a characteristic laugh. Apparently, he kept the x-ray department going by installing and servicing the developing tanks for x-ray film. Instead, he went full time at Westinghouse in Pittsburgh, where he earned a masters in physics at the University of Pittsburgh and a Ph.D. in Systems Science at Carnegie Mellon. His work there involved infrared detection devices for military use in night vision. "It was never successful," he says, "but interesting and pretty good physics." For a time, he worked in California at the Hughes Research Labs, and from his window in Malibu, he could watch whales spouting offshore. It was the time that Theodore Maiman shot off his first laser. Tom soon returned to Pittsburgh and Westinghouse to resume work on infra-red detection and design of optical systems with one of the 20th century's great lens designers, David Gray. The computer programs worked out at that time are still used by Japanese manufacturers in designing lenses for their cameras.
Colleagues from General Electric, Bell Labs, and he would jokingly agree when interviewing prospective employees that they would have everything a university can offer except the opportunity to grade papers. "Unfortunately, that's no longer true anywhere," he adds. From lenses, Tom switched to an interest in biological effects of light and its use in newborn infant jaundice. By now, Tom had become adjunct professor of pediatrics and radiology at Columbia College of Physicians and Surgeons, where he joined the study of babies with too much circulating yellow pigment, thus jaundice, due to insufficient metabolism in their immature liver system. The problem, if severe, causes brain damage and had plagued medical scientists for years.
"Actually [our work] came about through an interesting story [not related to this particular work]. My father, Alfred Vogl, as a resident physician in Vienna in the 30s, was responsible for the syphilitic ward. Mercurials [mercury] were the primary treatment at the time. Nurses were extremely meticulous, even about their records. They noticed after the mercury injections, the patients' urine output went up like crazy."
"Dr. Vogl became the father of mercurial diuretics," I conclude and Tom agrees. Ironically, a similar story developed around the observations by nurses in a London lying-in hospital, who noticed that jaundiced infants in the nursery occupying cribs next to the windows were always less jaundiced than the ones in the back of the room. Subsequently, doctors were able to demonstrate, first on rats, then on the babies themselves, that light rays hastened the decline in jaundice while waiting for the babies' livers to mature and take care of the problem naturally. Many were spared the more invasive and potentially dangerous treatment of exchange transfusions.
I am curious how Tom, without a medical degree, was received by medical colleagues after assuming the position of a professor of medicine. "It went very well. I had a grand time. Nominally, I was a full professor and had several graduate students in bio-engineering who were getting degrees under me. I was like a civilian being employed in the military with equal rank. I got a lot of papers written, over 150, I think.
"Oh, isn't this gorgeous!" Tom interrupts his steady stream of recollections. We have come suddenly out of the woods onto a small platform overlooking Vineyard Sound and the small curved beach and great rock beyond. During our walk, we have been aware of the steady beat of the wind through the fall leaves. The ground is littered. We stop a moment to read the inscription on a brass tablet honoring the Chilmark slave Rebecca, "Woman of Africa," along the African-American trail. I tell the story of how Rebecca's granddaughter became the mother of the first African-American whaling captain from Edgartown in the 19th century. Now we're ready to descend the steep stairs to the beach.
Although Tom left P&S before the light work was completed, he had had a hand in advancing that important tool in medicine. A National Academy of Sciences offer was too attractive to turn down, and he found himself in Washington, helping to write a report of work on photo-therapy. Later, he helped in the final report on toxicity of the anesthetic called halothane, which led to the replacement of that drug by better and safer agents ... "I left after four years. Not many people stayed that long."
We are now on the beach, with a long view east down-Island. Haze obscures the Elizabeths to a degree, but the views are spectacular. Tom stops to take a picture. We walk west along large, irregular stones and run the risk of breaking a leg, or worse. We retreat to the smooth sand and back up the stairs to the trail. Winded, we sit on a bench and catch our breaths. "Another funny story came out of my work on crystals at Westinghouse. This goes back a few decades," Tom begins. "It turns out that my name is on the original patent of the first temperature-sensing device, which has evolved into those strips of paper you stick on fish tanks to track temperature."
"And all the strips that mothers use to take babies' temperature?" I ask. "Oh, yes," he says. " I got a pat on the back, a framed certificate, and a dollar." We both laughed over his large reward. He was soon asked to be executive secretary of a national commission on digestive diseases at the National Institutes of Health (NIH), "the hardest work I ever did," he admits now. "Never home on weekends, but it was a good report and the field got more money [for research] out of it. I was too exhausted to look for another job, so I stayed on and helped run the interagency coordination on nutrition research, which was largely run out of President Carter's White House. In eight years, I figured I had about one year's experience. With new committee members each year, I would have to start explaining from scratch. I wanted to get back to doing my own research. Basically, I get bored every 10 or 15 years and need to change fields."
On the advice of a friend, Tom went to see Dan Alkon, who was working in a small unit of the NIH at the Marine Biological Laboratory in Woods Hole. "After sitting on a bench outside MBL, talking with Alkon for an afternoon about the biochemical and biophysical basis of learning, I decided 'now, that sounds like something I'd be interested in.'" His next 16 years were spent with both Office of Naval Research and NIH support, doing computer modeling of associative memory and memory at the cellular and subcellular level, having a grand time.
I am now well over my head in trying to understand where this research might go, and tell Tom so. "There has to be a permanent change in the brain of some sort, and that turns out to be a change in a neurotransmitter channel, commonly known by the initials GABA for gamma amino butyric acid. You cannot learn a fact. All you can have is an association of facts. The first facts are probably associations of feelings between intrauterine fetuses with their mothers - sounds, or touch through the mother's abdominal wall, and chemical changes within the uterus."
Another bench invites us to rest and talk of family and house hunting, our own stories of first arrival on the Vineyard. Tom's parents and brothers and sister escaped Nazi Germany in the mid 30s through Italy and England before finally coming to the United States just before Dunkirk, a year before Pearl Harbor. The elder Vogl's journey is a story in itself, getting out of Europe "by the skin of his teeth," repeating medical school in Edinburgh, finally establishing himself in practice, and for the rest of his life past 80 as professor of medicine at New York University and Mt. Sinai Hospital in New York.
As I leave my friend in West Tisbury, I think of the shelves of cookbooks back at the house. All those books! Tom's story comes back to me. "One day, Katherine found beet greens and squid in our refrigerator while planning dinner. We both remembered seeing a recipe including these items somewhere, but it took us two or three hours to find it. We decided then to catalogue all our recipes by ingredients. PCs were just coming out, and it took four months to find the software package we wanted. We now have 8,000 recipes on our hard drive. You can view the most delicious ones on our web site."
Our last conversation touches on Sept. 11 and the World Trade Center towers attack, but it is time today simply to enjoy this brief respite from bad news for a short time and look forward to winter solstice, the anniversary 21 years ago of Tom's and Katherine's first meeting. I can't wait to get back into their house, to explore once more.

 

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